Iron infusions spark warning as serious complication cases rise sharply
Cases of low blood phosphate from iron infusions rose to 46 in 2025 from 17 in 2020.
A dangerous drop in blood phosphate is becoming more common after iron infusions. This happens particularly among women of reproductive age.
The Therapeutic Goods Administration is now considering warning labels. The US already issued its strongest safety alert for this treatment.
Kate Russell, 46, ended up in an induced coma. An iron infusion caused her severe low blood phosphate.
Kate Russell experienced muscle weakness and irregular heartbeats but wasn't warned these were possible. The condition happens because the infusion blocks the kidneys' ability to recycle phosphate.
This causes dangerous levels to drop. Most patients recover within months with phosphate replacement therapy.
But the TGA has not yet confirmed whether Australia will follow the US warning.
- 46
- Hypophosphataemia cases in 2025
- 17
- Hypophosphataemia cases in 2020
- Kate Russell, 46 years old
- Patient in induced coma
- Toowoomba Hospital ICU
- Hospital location
Why it mattersAnyone considering iron infusions needs to know the real risks before treatment. Doctors need to check phosphate levels and discuss other options like oral iron tablets.
AustraliaThe TGA's decision on warning labels will affect thousands of Australians receiving iron infusions each year, particularly women dealing with anaemia or fatigue.
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